A facile, solvent and catalyst free, microwave assisted one pot synthesis of hydrazinyl thiazole derivatives

Abstract

A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used. This is an environmentally benign microwave assisted and efficient method for rapid synthesis of hydrazinyl thiazoles.

Keywords

• Cyclocondenzation
• Green synthesis
• Hydrazinyl thiazoles
• Aryl ketones
• α-Haloketones