Effect of Estrogen Receptor on the Relationship Between HER2 Immunohistochemistry Score and Pathological Complete Response to Neoadjuvant Treatment in HER2-Positive Breast Cancer

Miaomiao Jia; Haibo Yang; Lihui Pan; Jinnan Gao; Fan Guo

doi:10.1155/2024/8851703

The Breast Journal (Jan 2024)

Effect of Estrogen Receptor on the Relationship Between HER2 Immunohistochemistry Score and Pathological Complete Response to Neoadjuvant Treatment in HER2-Positive Breast Cancer

Miaomiao Jia,
Haibo Yang,
Lihui Pan,
Jinnan Gao,
Fan Guo

Affiliations

Miaomiao Jia: Department of Breast Surgery
Haibo Yang: Department of Breast Surgery
Lihui Pan: Department of Breast Surgery
Jinnan Gao: Department of Breast Surgery
Fan Guo: Department of Breast Surgery

DOI: https://doi.org/10.1155/2024/8851703
Journal volume & issue: Vol. 2024

Abstract

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Conclusion: HER2 IHC 2+ may indicate a decreased tpCR rate, bpCR rate, and apCR rate to neoadjuvant treatment in HR-positive patients having HER2-positive breast cancer, but not in HR-negative patients.

Published in The Breast Journal

ISSN: 1075-122X (Print); 1524-4741 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Medicine: Public aspects of medicine
Website: https://onlinelibrary.wiley.com/journal/tbj

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