Placental Pathology in Pregnancy-Induced hypertension

Abstract

Background: Hypertensive disorder in pregnancy is reflected in placenta in a significant way both macroscopically and microscopically. Study Design:A prospective observational study. Study setting:Pathology department in collaboration with the Obstetrics and Gynecology department at Qena university hospital, South Valley University, Qena, Egypt. Duration: From May 2019 to August 2020. Patients and method(s): This study was conducted on 50 cases of pregnant women with hypertension (mild, severe, eclampsia) and placental changes detected microscopically by H&E stain. Result(s): among 50 placentas studied, we found that infarction present in 16(59.3%) cases of mild hypertension, 10(62.5%) cases of severe hypertension and 7 (100.0%) cases of eclampsia. Calcification was found in 9(33.3%) cases of mild hypertension, 12(75.0%) cases of severe hypertension and 7(100.0%) cases of eclampsia. Conclusion: calcification and infarction were present in placenta of hypertensive pregnant women and increased with increased severity of hypertension.

Keywords

• pregnancy induced hypertension; placental pathology