Nature Communications (Oct 2021)
Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV
- Aljawharah Alrubayyi,
- Ester Gea-Mallorquí,
- Emma Touizer,
- Dan Hameiri-Bowen,
- Jakub Kopycinski,
- Bethany Charlton,
- Natasha Fisher-Pearson,
- Luke Muir,
- Annachiara Rosa,
- Chloe Roustan,
- Christopher Earl,
- Peter Cherepanov,
- Pierre Pellegrino,
- Laura Waters,
- Fiona Burns,
- Sabine Kinloch,
- Tao Dong,
- Lucy Dorrell,
- Sarah Rowland-Jones,
- Laura E. McCoy,
- Dimitra Peppa
Affiliations
- Aljawharah Alrubayyi
- Nuffield Department of Clinical Medicine, University of Oxford
- Ester Gea-Mallorquí
- Nuffield Department of Clinical Medicine, University of Oxford
- Emma Touizer
- Division of Infection and Immunity, University College London
- Dan Hameiri-Bowen
- Nuffield Department of Clinical Medicine, University of Oxford
- Jakub Kopycinski
- Nuffield Department of Clinical Medicine, University of Oxford
- Bethany Charlton
- Nuffield Department of Clinical Medicine, University of Oxford
- Natasha Fisher-Pearson
- Nuffield Department of Clinical Medicine, University of Oxford
- Luke Muir
- Division of Infection and Immunity, University College London
- Annachiara Rosa
- Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute
- Chloe Roustan
- Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute
- Christopher Earl
- Signalling and Structural Biology Laboratory, Francis Crick Institute
- Peter Cherepanov
- Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute
- Pierre Pellegrino
- Mortimer Market Centre, Department of HIV, CNWL NHS Trust
- Laura Waters
- Mortimer Market Centre, Department of HIV, CNWL NHS Trust
- Fiona Burns
- Institute for Global Health UCL
- Sabine Kinloch
- Royal Free London NHS Foundation Trust
- Tao Dong
- Nuffield Department of Clinical Medicine, University of Oxford
- Lucy Dorrell
- Nuffield Department of Clinical Medicine, University of Oxford
- Sarah Rowland-Jones
- Nuffield Department of Clinical Medicine, University of Oxford
- Laura E. McCoy
- Division of Infection and Immunity, University College London
- Dimitra Peppa
- Nuffield Department of Clinical Medicine, University of Oxford
- DOI
- https://doi.org/10.1038/s41467-021-26137-7
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 16
Abstract
Understanding the pathology and immunological response to SARS CoV2 infection in specific patient groups is essential for informing the scientific and clinical handling of infections within these patient populations. Here the authors characterise the adaptive immune response to SARS-CoV2 infection in people living with HIV.