In order to accurately predict the total organic carbon content of Middle Permian taodonggou group source rocks in Turpan Hami basin, based on the analysis of the relationship between logging parameters of multiple wells and organic matter abundance in the study area, the generalized Δlog R model is extended, that is, a generalized Δlog R model with spontaneous potential is proposed. It is found that the source rock in the study area has a weak positive correlation with resistivity density, a weak negative correlation with spontaneous potential, spontaneous gamma and density, and little correlation with neutrons. Compared with other methods, the correlation coefficient (R2) of the generalized Δlog R model with spontaneous potential is 0.804 2 and the average error rate is 15.58 %, which is the best method to predict the total organic carbon content of the source rocks of the Middle Permian Taodonggou group in the area. The results provide a basis for logging evaluation of source rocks in the study area.