Evaluation of Robinson's Cytological Grading of Breast Carcinoma and its Correlation with Elston-Ellis Modification of Scarff-Bloom-Richardson's Histological Grading

Abstract

Introduction: Fine Needle Aspirate (FNA) can serve as a valuable adjunct in cases of breast carcinoma by predicting cytological grading and guide the selection of appropriate therapy. Aim and Objectives: To evaluate the cytological grading in breast carcinoma cases by using Robinson’s grading and correlate it with Elston-Ellis modification of Scarff-Bloom-Richardson’s grading. Material and Methods: This study was carried out in the Department of Pathology, Bhagat Phool Singh Government Medical College for Women, Khanpur Kalan, Sonepat from 1st July 2015 to 30th June 2019. Fifty-one cases of breast carcinoma that underwent both fine needle aspiration and mastectomy were included. Robinson’s grading system was used for cytological grading and results were correlated with Scarff-Bloom-Richardson’s histological grading. Concordance rates, sensitivity and specificity were calculated. Results: The overall concordance rate between cytological and histological grading was 76.47%. Sensitivity was high in cytological Grade I tumors (83.33%) and least in cytological Grade III tumors (66.67%). Specificity was high in cytological Grade III tumors (94.29%) and least in cytological Grade II tumors (77.42%). Conclusion: Robinson’s cytological grading is easy, reproducible and correlates well with histological grade. It can be used routinely in predicting the prognosis and better management of patients as per the grade of tumor.

Keywords

• breast carcinoma
• prognosis
• robinson’s cytological grading
• scarff-bloom-richardson’s grading