A Highly Selective Turn-On Fluorescent Probe for the Detection of Zinc
Ling-Yi Shen,
Xiao-Li Chen,
Xian-Jiong Yang,
Hong Xu,
Ya-Li Huang,
Xing Zhang,
Carl Redshaw,
Qi-Long Zhang
Affiliations
Ling-Yi Shen
The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550014, China
Xiao-Li Chen
School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China
Xian-Jiong Yang
The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550014, China
Hong Xu
School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China
Ya-Li Huang
School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China
Xing Zhang
School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China
Carl Redshaw
Department of Chemistry, University of Hull, Cottingham Road, Hull, Yorkshire HU6 7RX, UK
Qi-Long Zhang
The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550014, China
A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification of Zn2+. 1H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe L. An emission titration experiment in the presence of different molar fractions of Zn2+ was used to perform a Job’s plot analysis. The results showed that the stoichiometric ratio of the complex formed by L and Zn2+ was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand L coordinates with one Cu atom in the asymmetric unit. On adding CuCl2 to the ZnCl2/L system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu2+ displaced Zn2+ to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe L.
