Clinical comparison of placental membrane versus platelet-rich fibrin membrane for treatment of gingival recession: A 2-year follow-up case report

Abstract

An amnion membrane is a placenta-derived tissue that has been introduced recently as a guided tissue regeneration membrane in dentistry. Numerous growth factors, proteins, and stem cell reserves in amnion could help in accelerated wound healing and regeneration. In addition, growth factors released after activation from the platelets in platelet-rich fibrin (PRF) gets trapped within fibrin matrix and also been shown to stimulate the mitogenic response in the periosteum for bone repair during normal wound healing. In this case report, a healthy 22-year-old male patient with bilateral Miller's Class I recession defects affecting canine were treated surgically with coronally advanced flap (CAF) along with amniotic membrane (AM) or PRF in a split-mouth design for coverage of the recession. Follow-up was done at baseline, 3 months, 6 months, and 18 months to evaluate the effectiveness of CAF with either PRF membrane or bioresorbable AM in the treatment of localized Miller's Class I gingival recession defects. This case report demonstrated that CAF + PRF and CAF + AM are equally effective in providing clinically significant outcomes in respect to root coverage with AM showing the better percentage of root coverage as compared to PRF. Thus, both the treatment modalities can be used for the coverage of gingival recession depending on the choice of clinician.

Keywords

• Amnion
• platelet-rich fibrin
• recession