MOLECULAR AND IMMUNOLOGICAL ASPECTS OF DENTAL DISEASES

Abstract

Inflammatory and neoplastic diseases are an important problem of dentistry, which was a prerequisite for a comprehensive detailed study of the etiology and pathogenesis of these nosologies from an immunobiological standpoint. Using the example of five factor models, the ratios of systemic and local immunity in chronic gingivitis, chronic periodontitis, leukoplakia, squamous cell carcinoma of the oral mucosa were revealed. The obtained data presented a continuum of transient immunological disorders with increased pathological changes in the tissues of the oral mucosa. Multivariate statistical analysis indicated the leading importance of mucosal immunity in the development of chronic inflammatory periodontal diseases, benign and malignant neoplasia of the epithelium of the oral cavity.

Keywords

• хроническое воспаление
• неоплазия
• рак
• слизистая оболочка
• иммунитет