Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (May 2019)

Prognostic Implications of Door‐to‐Balloon Time and Onset‐to‐Door Time on Mortality in Patients With ST‐Segment–Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

  • Jonghanne Park,
  • Ki Hong Choi,
  • Joo Myung Lee,
  • Hyun Kuk Kim,
  • Doyeon Hwang,
  • Tae‐Min Rhee,
  • Jihoon Kim,
  • Taek Kyu Park,
  • Jeong Hoon Yang,
  • Young Bin Song,
  • Jin‐Ho Choi,
  • Joo‐Yong Hahn,
  • Seung‐Hyuk Choi,
  • Bon‐Kwon Koo,
  • Shung Chull Chae,
  • Myeong Chan Cho,
  • Chong Jin Kim,
  • Ju Han Kim,
  • Myung Ho Jeong,
  • Hyeon‐Cheol Gwon,
  • Hyo‐Soo Kim

DOI
https://doi.org/10.1161/JAHA.119.012188
Journal volume & issue
Vol. 8, no. 9

Abstract

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Background In patients with ST‐segment–elevation myocardial infarction, timely reperfusion therapy with door‐to‐balloon (D2B) time 90 minutes (adjusted hazard ratio, 0.30; 95% CI, 0.19–0.42; P<0.001). Every reduction of D2B time by 30 minutes showed continuous reduction of 1‐year mortality (90 to 60 minutes: absolute risk reduction, 2.4%; number needed to treat, 41.9; 60 to 30 minutes: absolute risk reduction, 2.0%; number needed to treat, 49.2). Conclusions Shortening D2B time was significantly associated with survival benefit, and the survival benefit of shortening D2B time was consistently observed, even <60 to 90 minutes.

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