Age-associated features of recovery and maintenance of the vaginal microbiota in the therapy of the female genital tract infections

Abstract

Vaginal biotope is a dynamically changing in structure microecosystem depending on the woman's age, menstrual cycle, pregnancy and other factors. In reproductive age the most common infections of the female lower genital tract are bacterial vaginosis, vulvovaginal candidiasis, aerobic vaginitis, mixed infections and sexually transmitted diseases. In post-menopausal period urogenital disorders form in genitourinary syndrome. Independently of age urogenital infections accompanied with damage of vaginal epithelium and decreased lactobacilli level. In a brief review is discussed the rationale pathogenetic therapy aimed at restoring the vaginal epithelium and maintain the growth of lactobacilli in the vagina. Data for the efficiency use vaginal tablets containing Lactobacillus acidophilus KS400 estriol and 0.03 mg per tablet (for 6 days in the reproductive years and at least 12 days - in postmenopause) for these purposes are presented.

Keywords

• vaginal infections
• lactobacilli
• estriol
• maintenance therapy