Nature Communications (Sep 2022)

The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems

  • Keren Lasker,
  • Steven Boeynaems,
  • Vinson Lam,
  • Daniel Scholl,
  • Emma Stainton,
  • Adam Briner,
  • Maarten Jacquemyn,
  • Dirk Daelemans,
  • Ashok Deniz,
  • Elizabeth Villa,
  • Alex S. Holehouse,
  • Aaron D. Gitler,
  • Lucy Shapiro

DOI
https://doi.org/10.1038/s41467-022-33221-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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“Intracellular phase separation is emerging as a universal principle for organizing biochemical reactions in time and space. Here the authors show that PopZ condensate dynamics support cell division and using PopZ modular architecture, the tunable PopTag platform was developed to enable designer condensates.”