Impaired carbohydrate tolerance as a risk factor for ischemic heart disease among the population of the Fergana Valley of the Republic of Uzbekistan

Abstract

In the Fergana Valley of the Republic of Uzbekistan, where about 70% of the population is engaged in agriculture, epidemiological studies on IHD in connection with the combination of risk factors among rural men and women of working age have not been carried out, which makes it impossible to fully assess the epidemiological situation in our region. The aim of the research was to study the epidemiological conditions in relation to IHD in connection with ICT and other risk factors. To identify IHD and risk factors, we chose a continuous method of epidemiological examination using the Rose questionnaire, blood pressure measurements, ECG decoding according to the Minnesota code, glucose tolerance test, anthropometric and biochemical studies. When analyzing the prevalence of IHD in the quintile distribution of risk factors among men and women, a high correlation was found with an increase in blood glucose levels on an empty stomach and 2 hours after exercise. To determine the group for the prevention of IHD, we used a logistic model that allows us to calculate the individual risk, considering the presence and potential of risk factors. Evaluation of the informativeness of each risk factor showed that both in men and women, ICT has the highest prognostic value for IHD. In a mass survey of the rural population of the Fergana Valley, to identify IHD and the contingent “threatened” in relation to IHD, it is necessary to widely conduct a carbohydrates tolerance test.