Human Pathology Reports (Mar 2023)

Malignant hyperthermia: A case report

  • Fereshteh Amiri,
  • Mahbobeh Rashidi,
  • Mohsen Savaei

DOI
https://doi.org/10.1016/j.hpr.2023.300693
Journal volume & issue
Vol. 31
p. 300693

Abstract

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Malignant hyperthermia is a rare hypermetabolic pharmacogenetic pathologic disorder of calcium release control in skeletal muscle following exposure to depolarizing muscle relaxants and inhalational anesthetics in general anesthesia. This report describes the case of a 32-year-old man undergoing emergency laparotomy after being shot in the stomach. The patient suffered a malignant hyperthermia attack following the administration of Succinylcholine to induce anesthesia and Isoflurane to maintain anesthesia. Eventually, we were able to treat the patient for malignant hyperthermia successfully.

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