Nature Communications (Sep 2017)

The brain is required for normal muscle and nerve patterning during early Xenopus development

  • Celia Herrera-Rincon,
  • Vaibhav P. Pai,
  • Kristine M. Moran,
  • Joan M. Lemire,
  • Michael Levin

DOI
https://doi.org/10.1038/s41467-017-00597-2
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 18

Abstract

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Functions of the embryonic brain prior to regulating behavior are unclear. Here, the authors use an amputation assay in Xenopus laevis to demonstrate that removal of the brain early in development alters muscle and peripheral nerve patterning, which can be rescued by modulating bioelectric signals.