Antimicrobial and Anti-Biofilm Effects of Mentha piperita and Zataria multiflora on Pathogenic Bacteria

Abstract

Background: The aim of this study was to investigate the antimicrobial and anti-biofilm effects of Mentha piperita and Zataria multiflora on some pathogenic bacteria. Methods: Mentha piperita and Zataria multiflora essential oils were obtained by using the clevenger device. The bacterial cultures were prepared as standard samples. Finally, antimicrobial and anti-biofilm activity was determined by microdilution method. Results: The results of this study showed that the lowest inhibitory concentration of essential oil of Zataria multiflora was 1.25 mg / ml, while the rest of the bacteria were inhibited at a concentration of 2.5 mg / ml. The lowest and highest inhibitory concentrations were found as 1.25 and 5 mg / ml against Pseudomonas aeruginosa. Conclusion:The results of the study showed that Z. multiflora essential oil showed antimicrobial and anti-biofilm activity that could be used to treat infections caused by these bacteria.

Keywords

• Antibacterial activity
• Anti biofilm activity
• Essential oil
• Pathogen.