Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism

Abstract

The biogenesis of eukaryotic ribosomes is a multi-step process involving the action of more than 200 different ribosome assembly factors. Here the authors show that Rps20 acts as a conduit to coordinate maturation steps across the head domain of the nascent small ribosomal subunit.