Detection of a Multiple Circulation Event of Dengue Virus 2 Strains in the Northern Region of Brazil

Murilo Tavares Amorim; Felipe Gomes Naveca; Leonardo Henrique Almeida Hernández; Thito Yan Bezerra da Paz; Cintia Cryslaine da Silva de Oliveira; Alessandra da Conceição Miranda Santos; Alice Louize Nunes Queiroz; Ana Lucia Monteiro Wanzeller; Eliana Vieira Pinto da Silva; Fábio Silva da Silva; Sandro Patroca da Silva; Bruno Tardelli Diniz Nunes; Ana Cecília Ribeiro Cruz

doi:10.3390/tropicalmed9010017

Tropical Medicine and Infectious Disease (Jan 2024)

Detection of a Multiple Circulation Event of Dengue Virus 2 Strains in the Northern Region of Brazil

Murilo Tavares Amorim,
Felipe Gomes Naveca,
Leonardo Henrique Almeida Hernández,
Thito Yan Bezerra da Paz,
Cintia Cryslaine da Silva de Oliveira,
Alessandra da Conceição Miranda Santos,
Alice Louize Nunes Queiroz,
Ana Lucia Monteiro Wanzeller,
Eliana Vieira Pinto da Silva,
Fábio Silva da Silva,
Sandro Patroca da Silva,
Bruno Tardelli Diniz Nunes,
Ana Cecília Ribeiro Cruz

Affiliations

Murilo Tavares Amorim: Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, Brazil
Felipe Gomes Naveca: Laboratory of Infectious Diseases Ecology in Amazon, Leonidas and Maria Deane Institute, Fiocruz, Manaus 69057-070, Brazil
Leonardo Henrique Almeida Hernández: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Thito Yan Bezerra da Paz: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Cintia Cryslaine da Silva de Oliveira: Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, Brazil
Alessandra da Conceição Miranda Santos: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Alice Louize Nunes Queiroz: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Ana Lucia Monteiro Wanzeller: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Eliana Vieira Pinto da Silva: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Fábio Silva da Silva: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Sandro Patroca da Silva: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Bruno Tardelli Diniz Nunes: Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil
Ana Cecília Ribeiro Cruz: Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, Brazil

DOI: https://doi.org/10.3390/tropicalmed9010017
Journal volume & issue: Vol. 9, no. 1
p. 17

Abstract

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Dengue virus serotype 2 (DENV-2) is responsible for dengue epidemics on a global scale and is associated with severe cases of the disease. This study conducted a phylogenetic investigation of DENV-2 isolates from 2017 to 2021 originating from the northern states of Brazil. A total of 32 samples from DENV-2 isolates were analyzed, including 12 from Acre, 19 from Roraima, and one from Tocantins. Only one lineage of the Asian-American genotype and one lineage of the cosmopolitan genotype were observed: Lineage 1, Asian-American genotype (connection to Puerto Rico); Lineage 5, cosmopolitan genotype (connection to Peru). Our results provide important data regarding the study of DENV genotypes and lineage distribution and open up possibilities for probable introduction and dissemination routes.

Published in Tropical Medicine and Infectious Disease

ISSN: 2414-6366 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/tropicalmed

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