European Journal of Case Reports in Internal Medicine (Feb 2021)

Sarcoidosis Versus Lymphoma?

  • Lissandra Dal Lago,
  • Julie Sarrand,
  • Erwin Woff,
  • Ahmad Awada,
  • Michaël Vouche,
  • Thierry Pepersack

DOI
https://doi.org/10.12890/2021_002250

Abstract

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An association between lymphoma and sarcoidosis was first suggested in 1960. We report a case of sarcoidosis-lymphoma syndrome, which is a diagnostically challenging condition. We conclude that an associated lymphoma should be considered in all patients with suspected sarcoidosis, especially those who do not respond to treatment or who present with persistent haematological abnormalities. Splenomegaly should prompt splenectomy to rule out lymphoma if a less invasive approach has failed to confirm the diagnosis.

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