Communications Chemistry (Mar 2021)

Iodine(III) promotes cross-dehydrogenative coupling of N-hydroxyphthalimide and unactivated C(sp3)–H bonds

  • Fufang Wu,
  • Xuanzhen Han,
  • Xuejian Li,
  • Xiaobao Shen,
  • Chang Wang,
  • Zhimei Tian,
  • Bin Cheng,
  • Jingbin Zhang,
  • Liangquan Sheng,
  • Hongbin Zhai

DOI
https://doi.org/10.1038/s42004-021-00480-8
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 7

Abstract

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Robust and selective C–H functionalisation of alkanes remains a challenge. Here, iodine(III) mediates the radical coupling of N-hydroxyphthalimide and unactivated C(sp3)–H bonds in a range of cyclic and acyclic alkanes.