Texas Heart Institute Journal (Aug 2025)

Lyme Carditis and Inflammation-Driven Plaque Erosion Presenting as Sudden Cardiac Arrest

  • Marco Kaldas, MD,
  • Moneal Shah, MD,
  • Diana Pashaieva, BDS,
  • Georgios Lygouris, MD,
  • Anita Radhakrishnan, MD

DOI
https://doi.org/10.14503/thij-24-8543
Journal volume & issue
Vol. 52, no. 2
pp. 1 – 7

Abstract

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Lyme carditis represents a rare cardiac complication of Borrelia burgdorferi infection, often causing conduction disturbances but rarely causing malignant arrhythmias. Inflammatory acute coronary syndrome, driven by immune-mediated plaque erosion rather than rupture, represents a nontraditional ischemic mechanism. This case highlights their overlap. The case of a previously healthy man with Lyme disease who experienced cardiac arrest because of ventricular tachycardia is reported. Imaging showed myocardial inflammation together with coronary plaque erosion instead of plaque rupture. The patient underwent advanced diagnostic testing and received multidisciplinary medical care, which led to complete cardiac recovery and implantable cardioverter-defibrillator placement.

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