Mycochemical Constituents and Anti-Inflammatory Activity of <i>Terfezia claveryi</i> Chatin from Algeria

Abstract

Mushrooms are receiving particular attention as a new source of valuable biotherapeutics. The aim of the current study is the valorization of Terfezia claveryi Chatin from Algeria. The mycochemical constituents, polyphenol, flavonoid and condensed tannin composition and the in vitro anti-inflammatory activity were examined using the heat denaturation protein inhibition method. Mycochemical tests presented very interesting richness in terms of secondary metabolites, and the polyphenol, flavonoid and condensed tannin contents of the hydro-methanol extract were, respectively, 82.27 ± 1.44 µg GAE/mg, 14.94 ± 0.98 µg CE/mg, and 27.50 ± 2.50 µg CE/mg. The extract at the 1.5 mg/mL level showed an inhibition of denaturation of 83.53 ± 1.57% compared to diclofenac sodium (98.43 ± 0.52%). This research revealed Terfezia claveryi’s interesting anti-inflammatory properties, which confirms its value in traditional use.

Keywords

• <i>Terfezia claveryi</i>
• mycochemical constituents
• anti-inflammatory activity