Comparative Study of Magnesium Sulfate and Phenytoin in Prevention of Convention in Pre-Eclamptic Patients

Abstract

Pre-eclampsia is one of the common complications in pregnancy and it is one of three causes of maternal mortality. The major cause of death in pre-eclampsia is adding convulsion and change to eclampsia. My sulfate is choice drug for prevention of convulsion in pre-eclampsia. Another recommended drug is phenytoin. Each of these drugs have benefits and disadvantages. In this study by R.C.T procedure 60 pre-eclamptic patients divided in two randomized groups. 30 patients took phenytoin and 30 patients took Mg sulfate. In Mg sulfate group one case had convulsion (F. R 3.3%) and in phenytoin group, two cases had convulsion (F. R: 6.6%). There was no significant difference with X2 test between two drugs in anti-convulsion effect.

Keywords

• magnesium sulfate / phenytoin / pre-eclampsia