Association of Helicobacter pylori specific IgG antibody with serum magnesium levels in peritoneal dialysis patients

Abstract

Introduction: Few studies have reported the relationship between serum magnesium and Helicobacter pylori infection in chronic kidney disease (CKD) and patients receiving dialysis. Objectives: In this study, we aimed to test, the relationship between serum magnesium (Mg) level and H. pylori infection in CKD patients receiving peritoneal dialysis. Patients and methods: Around 40 patients were evaluated through the study. Serum magnesium levels and H. pylori specific IgG antibody levels were assessed. Results: The mean serum magnesium level was 3.00 ± 0.36 mg/dL. No significant difference was seen in serum Mg level between positive and negative groups of H. pylori. No correlations were reported between H. pylori IgG titers with age, serum Mg, Ca, P, parathyroid hormone (PTH), vitamin D, albumin, urea, creatinine (Cr) and plasma hemoglobin (P>0.05). Conclusion: In this study no correlation between serum magnesium levels and H. pylori specific IgG antibody was detected. We believe that this is the first study evaluating the relationship between serum magnesium level and H. pylori infection in peritoneal dialysis patients. More and larger clinical investigations are required to consider the conflicting results of studies regarding the association of serum magnesium and H. pylori in patients undergoing dialysis.

Keywords

• Magnesium
• Helicobacter pylori
• Peritoneal dialysis