Bio-Protocol (Sep 2013)

Generation of Mouse Spinal Cord Injury

  • Oneil Bhalala,
  • Liuliu Pan,
  • Hilary North,
  • Tammy McGuire,
  • John Kessler

DOI
https://doi.org/10.21769/BioProtoc.886
Journal volume & issue
Vol. 3, no. 17

Abstract

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Spinal cord injury (SCI) is a debilitating injury with significant morbidity and mortalitiy. Understanding the pathogensis of and developing treatments for SCI requires robust animal models. Here we describe a method for generating an efficient and reproducible contusion model of SCI in adult mice.