Nature Communications (Jan 2023)

Decision level integration of unimodal and multimodal single cell data with scTriangulate

  • Guangyuan Li,
  • Baobao Song,
  • Harinder Singh,
  • V. B. Surya Prasath,
  • H. Leighton Grimes,
  • Nathan Salomonis

DOI
https://doi.org/10.1038/s41467-023-36016-y
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

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Single-cell genomics has expanded to measure diverse molecular modalities within the same cell. Here the authors provide a computational framework called scTriangulate to integrate cluster annotations from diverse independent sources, algorithms, and modalities to define statistically stable populations.