Nature Communications (Nov 2021)

Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging

  • Hela Benaissa,
  • Karim Ounoughi,
  • Isabelle Aujard,
  • Evelyne Fischer,
  • Rosette Goïame,
  • Julie Nguyen,
  • Alison G. Tebo,
  • Chenge Li,
  • Thomas Le Saux,
  • Giulia Bertolin,
  • Marc Tramier,
  • Lydia Danglot,
  • Nicolas Pietrancosta,
  • Xavier Morin,
  • Ludovic Jullien,
  • Arnaud Gautier

DOI
https://doi.org/10.1038/s41467-021-27334-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

Read online

Fluorescent reporters spanning the visible spectrum are needed for imaging live cells and organisms. Here the authors report a collection of fluorogenic chromophores that cover the visible spectrum from blue to red using a single engineered and optimised protein tag.