DIVERSITY OF ANTIMICROBIAL RESISTANCE MECHANISMS IN SALMONELLA

Abstract

Abstract. Current review presents information on the antimicrobial resistance of Salmonella of various serotypes. The phenotypes of resistance and the main resistance mechanisms to the antimicrobials of various groups are described. Comparison data on the resistance to antimicrobials of Salmonella serological variants, which circulate worldwide including the Russian Federation (S. Typhimurium DT104, S. Newport, S. Virchow, S. Enteritidis) are shown. Moreover, epidemiological characteristics of transmission factors related to these pathogens are discussed. Special attention is given to genetic determinants, which encode the resistance of Enterobacteriaceae, as well as mobile genetic elements (integrons, plasmids, pathogenicity islands), which are involved in the spread of resistance.

Keywords

• salmonella
• resistance
• antimicrobials
• quinolones
• β-lactamase