Pre-ribosomal particles from nucleoli to cytoplasm

Abstract

The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the focus of advanced microscopic approaches. Recently, it has been possible to identify and visualize individual pre-ribosomal particles on their way through the nuclear pore complex using both electron and light microscopy. In this review, we focused on the transport of pre-ribosomal particles in the nucleus on their way to and through the pores.

Keywords

• Electron tomography
• fluorescence microscopy
• intranuclear mobility
• localization precision
• nucleocytoplasmic transport
• RNA export