Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester

• Miao Xiao,
• Qiaoli Shang,
• Liuyang Pu,
• Zheyuan Wang,
• Lei Zhu,
• Zhen Yang,
• Jun Huang

Affiliations

Miao Xiao

School of Chemistry and Chemical Engineering, University of South China, Hengyang, China

Qiaoli Shang

School of Chemistry and Chemical Engineering, University of South China, Hengyang, China

Liuyang Pu

School of Chemistry and Chemical Engineering, University of South China, Hengyang, China

Zheyuan Wang

State Key Laboratory of Chemical Oncogenomics and Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China

Lei Zhu

College of Pharmacy, Third Military Medical University, Chongqing, China

Zhen Yang

State Key Laboratory of Chemical Oncogenomics and Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China

Jun Huang

School of Chemistry and Chemical Engineering, University of South China, Hengyang, China