Virulence (Dec 2022)

Do B-1 cells play a role in response to Mycobacterium tuberculosis Beijing lineages?

  • Fermín Acosta,
  • Patricia L. Fernández,
  • Amador Goodridge

DOI
https://doi.org/10.1080/21505594.2021.2003116
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 4

Abstract

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We highlight the need to include an analysis of the B-1 B cell subset to complement the characterization of the cell-mediated immune response to the Mycobacterium tuberculosis Beijing lineage. The literature describes the B-1 cell repertoire’s involvement in the cell-mediated response within granulomas, which is different from the classic antibody response B cells are generally associated with. Specifically, the B-1 B cell subset migrates from other compartments along with other cells to the infection site. We provide details to complement the reported results from Cerezo-Cortes et al.

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