Nature Communications (Sep 2019)

Circadian control of lung inflammation in influenza infection

  • Shaon Sengupta,
  • Soon Y. Tang,
  • Jill C. Devine,
  • Seán T. Anderson,
  • Soumyashant Nayak,
  • Shirley L. Zhang,
  • Alex Valenzuela,
  • Devin G. Fisher,
  • Gregory R. Grant,
  • Carolina B. López,
  • Garret A. FitzGerald

DOI
https://doi.org/10.1038/s41467-019-11400-9
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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The circadian clock affects immune responses, but its role in influenza infection is not well understood. Here, Sengupta et al. show that time of infection and the circadian clock have no effect on lung virus titers, but affect inflammation, morbidity and mortality.