Paired logistic regression analysis of influencing factors for vascular crisis after repair of oral and maxillofacial tumors with free tissue flaps

Abstract

Objective To investigate the influencing factors of vascular crisis after oral and maxillofacial tumor free tissue flap transplantation. Methods A retrospective analysis was performed on all patients who underwent free tissue flap transplantation and developed vascular crisis in the surgical ward of head and neck cancer in a grade A specialized hospital. Forty-six possible influencing factors were collected using 1:1 matching according to surgeons, operation time, sex and age of patients from patients without vascular crisis from 2015-2020 in this ward during the same period. SPSS 26.0 statistical software was used for univariate and multivariate logistic regression analyses of the data. Results A total of 158 patients were enrolled, including 79 in the crisis group and 79 in the pairing group. Univariate analysis was performed for each variable. Paired logistic regression analysis showed that only postoperative blood potassium (P = 0.048, OR = 3.118, 95% CI: 1.008-9.641) and preoperative and postoperative red blood cell count differences (P = 0.004, OR = 4.53, 95% CI: 1.609-12.750) were statistically significant. Conclusion High blood potassium levels and red blood cell count differences before and after surgery were risk factors for vascular crisis.

Keywords

• oral maxillofacial
• oral cancer
• free tissue flap
• transplantation
• vascular crisis
• arterial crisis
• vein crisis
• influencing factors
• blood potassium
• red blood cell count