Clinical Ophthalmology (Feb 2020)

532-nm Subthreshold Micropulse Laser for the Treatment of Chronic Central Serous Retinopathy

  • Sousa K,
  • Calvão-Santos G,
  • João M,
  • Gomes N,
  • Falcão M

Journal volume & issue
Vol. Volume 14
pp. 525 – 531

Abstract

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Keissy Sousa,1 Gil Calvão-Santos,1 Marina João,2 Nuno Gomes,1 Manuel Falcão3,4 1Retina Department of Hospital de Braga, Braga, Portugal; 2Ophthalmology Department of Hospital de Braga, Braga, Portugal; 3Retina Department of Centro Hospitalar Universitário S. João, Porto, Portugal; 4Department of Surgery and Physiology of Faculty of Medicine of the University of Porto, Porto, PortugalCorrespondence: Manuel FalcãoOftalmologia, Centro Hospitalar S. João, Alameda Prof. Hernâni Monteiro, Porto 4200-319, PortugalTel +351 22 551 2100Email [email protected]: Subthreshold micropulse laser treatment with a 532 nm (532-SML) wavelength has been suggested as a treatment option for the treatment of chronic central serous retinopathy (cCSR). The objective is to present its effects and complications.Methods: We present a retrospective cohort study of cCSR patients submitted to 532-SML. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT) parameters – central macular thickness, subfoveal outer nuclear layer, external limiting membrane, ellipsoid band, interdigitation band, subretinal fluid and choroidal thickness – were evaluated before and 12 weeks after treatment. A power of 50%, a duty cycle of 5%, exposure time of 200 ms and a spot size of 160 μm were the applied laser parameters.Results: We included 26 eyes. Overall there were no significant changes in visual acuity (median 0.20 (IQR 0) logMAR before and after treatment) or SD-OCT parameters. However, visual benefits occurred in 42.3% (n=11) of the patients and in half of the cases, subretinal fluid was completely reabsorbed. There were no complications.Conclusion: In this study,  532-SML was overall ineffective on cCSR as it did not lead to significant changes in the overall median visual acuity and SD-OCT parameters. However, some patients may have benefited functionally and anatomically from the treatment; further investigation is necessary to understand the potential of 532-SML.Keywords: central serous retinopathy, SD-OCT, subthreshold micropulse laser, 532 nm wavelength, outer retina bands

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