METABOLIC ACTIVITY STUDY IN PEOPLE WITH DRUG ALLERGY USING «COCKTAIL» PHENOTYPING METHOD

Abstract

Study of main CYP isoforms activity using «cocktail» method was conducted on patients suffered from drug allergy with different concurrent diseases in order to determine the presence of correlation between drug allergy appearance and changes in biotransformation activity.

Keywords

• cytochrome p450
• cyp
• «cocktail» method
• phenotyping
• drug allergy