Modern aspects of the pathogenetic therapy of osteoarthritis

Abstract

The article details the risk factors, mechanisms of pathogenesis and progression of osteoarthritis. The role of chondroprotectors in the multimodal treatment of the disease is discussed; study results on the effectiveness of glucosamine and chondroitin sulfate are provided which evidence their value in the treatment of osteoarthritis.

Keywords

• остеоартроз
• дегенерация суставного хряща
• симптом-модифицирующие препараты замедленного действия
• хондроитина сульфат
• глюкозамина сульфат
• osteoarthritis
• degeneration of articular cartilage
• slow-acting symptom-modifying drugs
• chondroitin sulfate
• glucosamine sulfate