Novel Screen-Printed Sensor with Chemically Deposited Boron-Doped Diamond Electrode: Preparation, Characterization, and Application
Oleksandr Matvieiev,
Renáta Šelešovská,
Marian Vojs,
Marián Marton,
Pavol Michniak,
Vojtěch Hrdlička,
Michal Hatala,
Lenka Janíková,
Jaromíra Chýlková,
Jana Skopalová,
Petr Cankař,
Tomáš Navrátil
Affiliations
Oleksandr Matvieiev
Institute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic
Renáta Šelešovská
Institute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic
Marian Vojs
Institute of Electronics and Photonics, Faculty of Electrical Engineering and Information Technology, Slovak University of Technology in Bratislava, Ilkovičova 3, 812 19 Bratislava, Slovakia
Marián Marton
Institute of Electronics and Photonics, Faculty of Electrical Engineering and Information Technology, Slovak University of Technology in Bratislava, Ilkovičova 3, 812 19 Bratislava, Slovakia
Pavol Michniak
Institute of Electronics and Photonics, Faculty of Electrical Engineering and Information Technology, Slovak University of Technology in Bratislava, Ilkovičova 3, 812 19 Bratislava, Slovakia
Vojtěch Hrdlička
J. Heyrovsky Institute of Physical Chemistry of the Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23 Prague, Czech Republic
Michal Hatala
Department of Graphic Arts Technology and Applied Photochemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, 812 37 Bratislava, Slovakia
Lenka Janíková
Institute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic
Jaromíra Chýlková
Institute of Environmental and Chemical Engineering, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic
Jana Skopalová
Department of Analytical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 1192/12, 779 00 Olomouc, Czech Republic
Petr Cankař
Department of Organic Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 1192/12, 779 00 Olomouc, Czech Republic
Tomáš Navrátil
J. Heyrovsky Institute of Physical Chemistry of the Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23 Prague, Czech Republic
New screen-printed sensor with a boron-doped diamond working electrode (SP/BDDE) was fabricated using a large-area linear antenna microwave chemical deposition vapor system (LA-MWCVD) with a novel precursor composition. It combines the advantages of disposable printed sensors, such as tailored design, low cost, and easy mass production, with excellent electrochemical properties of BDDE, including a wide available potential window, low background currents, chemical resistance, and resistance to passivation. The newly prepared SP/BDDEs were characterized by scanning electron microscopy (SEM) and Raman spectroscopy. Their electrochemical properties were investigated by cyclic voltammetry and electrochemical impedance spectroscopy using inner sphere ([Fe(CN)6]4−/3−) and outer sphere ([Ru(NH3)6]2+/3+) redox probes. Moreover, the applicability of these new sensors was verified by analysis of the anti-inflammatory drug lornoxicam in model and pharmaceutical samples. Using optimized differential pulse voltammetry in Britton–Robinson buffer of pH 3, detection limits for lornoxicam were 9 × 10−8 mol L−1. The oxidation mechanism of lornoxicam was investigated using bulk electrolysis and online electrochemical cell with mass spectrometry; nine distinct reaction steps and corresponding products and intermediates were identified.
