Nature Communications (May 2020)

Critical slowing down as a biomarker for seizure susceptibility

  • Matias I. Maturana,
  • Christian Meisel,
  • Katrina Dell,
  • Philippa J. Karoly,
  • Wendyl D’Souza,
  • David B. Grayden,
  • Anthony N. Burkitt,
  • Premysl Jiruska,
  • Jan Kudlacek,
  • Jaroslav Hlinka,
  • Mark J. Cook,
  • Levin Kuhlmann,
  • Dean R. Freestone

DOI
https://doi.org/10.1038/s41467-020-15908-3
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Critical slowing (associated with increased variance and autocorrelation) can precede critical state transitions. Here, the authors show critical slowing can be used as a marker in seizure forecasting algorithms.