Menopause Review (Apr 2011)
Rak trzonu macicy u kobiet po 70. roku życia. Ocena wczesnego ostrego odczynu popromiennego
Abstract
Objectives: The objective of the study was to evaluate the tolerance of radical radiotherapy in patients withcancer of the corpus uteri, aged 70 years and older. Materials and methods: The analysis is based on 94 patients with cancer of the corpus uteri. There were94 women aged 70-85 years (median 74 years) treated using radical radiotherapy in the Department of Radiotherapy,Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Gliwice Branch in Polandduring 2008 to October 2010. Acute treatment toxicity was assessed using the EORTC/RTOG scale. The skinreaction, the digestive system reaction and urinary tract reaction were analysed. Results: The most frequent early acute post-radiation reaction was bowel reaction (74.5%) in comparisonwith skin (24.5%) and urinary bladder (15.96%) reactions. A severe bowel reaction, adynamic ileus, was observedin 4 patients. There were no severe reactions of the urinary bladder. Benign reactions of the bladder were observedin 15 patients (15.96%). Severe skin reactions in 1 (1.06%) patient and benign reaction in 22 (23.4%) wereobserved. In the majority of patients there were no skin reaction (75.5%). Conclusion: Radical radiotherapy in senile patients with cancer of the corpus uteri is combined with higherfrequency of early acute toxicity, but still remains a safe and well-tolerated method of treatment.
