PLoS ONE (Jan 2019)

Effect of time interval from diagnosis to treatment for cervical cancer on survival: A nationwide cohort study.

  • Chao-Ping Chen,
  • Pei-Tseng Kung,
  • Yueh-Hsin Wang,
  • Wen-Chen Tsai

DOI
https://doi.org/10.1371/journal.pone.0221946
Journal volume & issue
Vol. 14, no. 9
p. e0221946

Abstract

Read online

OBJECTIVES:Despite the ease of health care access and the waiver of copayments for cancer patients, treatment is delayed in a small proportion of Taiwanese patients diagnosed with cervical cancer. In this study, we explored the relationship between the time interval from diagnosis to treatment and survival in cervical cancer patients. MATERIAL AND METHODS:The study was a retrospective population-based observational study conducted between 2004 and 2010. In Taiwan, 12,020 patients were newly diagnosed with cervical cancer from 2004 to 2010, and 9,693 patients (80.6%) were enrolled in our final analysis. RESULTS:Most of the patients received treatment within 90 days of diagnosis (n = 9,341, 96.37%). After adjustment for other variables, patients who received treatment between 90 and 180 days and >180 days after diagnosis had a 1.33 (95% CI: 1.02-1.72, P 180 days after diagnosis. CONCLUSION:A longer interval between diagnosis and treatment is associated with poorer prognosis among cervical cancer patients.