An in vivo study to determine the efficacy of lycopene as compared to multivitamin preparation in the treatment of oral submucous fibrosis

Abstract

Objectives: The study was conducted to assess the efficacy of lycopene in the treatment of oral submucous fibrosis (OSMF) among patients visiting Dental College in Jaipur, Rajasthan, aged 15 years and above. Materials and methods: Twenty OSMF patients were randomly divided into two groups A and B. Group A, patients received combination of lycopene (16 mg) in divided doses. Group B, patients received combination of multivitamin preparation. Treatment outcome was evaluated on the basis of improvement in symptom score, sign score. The statistical analysis was done with SPSS software, version 11.5. Results: The result showed that OSMF patients receiving lycopene have more improvement in burning sensation and with some improvement in mouth opening. Conclusion: The observations and findings of the study clearly indicate that efficacy of lycopene is higher compared to multivitamin preparation.

Keywords

• Treatment
• Oral submucous fibrosis
• Lycopene
• Multivitamin preparation