Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans

Kiyomi Raye Kaneshiro; Andreas Rechtsteiner; Susan Strome

doi:10.1038/s41467-019-09141-w

Nature Communications (Mar 2019)

Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans

Kiyomi Raye Kaneshiro,
Andreas Rechtsteiner,
Susan Strome

Affiliations

Kiyomi Raye Kaneshiro: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz
Andreas Rechtsteiner: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz
Susan Strome: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz

DOI: https://doi.org/10.1038/s41467-019-09141-w
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 9

Abstract

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The mechanisms of paternal epigenetic inheritance and its influence on offspring are still poorly understood. Here the authors provide evidence that in C. elegans, sperm-inherited chromatin states influence transcription and cell identity in the germ cells of offspring.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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