Journal of Clinical Medicine (May 2024)

Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours

  • Jodie L. M. Tham,
  • Sweet Ping Ng,
  • Richard Khor,
  • Morikatsu Wada,
  • Hui Gan,
  • Alesha A. Thai,
  • June Corry,
  • Houda Bahig,
  • Antti A. Mäkitie,
  • Sandra Nuyts,
  • Remco De Bree,
  • Primož Strojan,
  • Wai Tong Ng,
  • Avraham Eisbruch,
  • James C. H. Chow,
  • Alfio Ferlito

DOI
https://doi.org/10.3390/jcm13113020
Journal volume & issue
Vol. 13, no. 11
p. 3020

Abstract

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The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.

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