Estimation of reproductive toxicity of the complex plant remedy "Tireoton"

Abstract

To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the "Tireoton" at the doses of 75 and 750 mg/kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the "Tireoton" at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny.

Keywords

• potentilla alba l
• scutellaria baicalensis georgi
• rhodiola rosea l
• complex plant remedy
• potentilla alba l
• scutellaria baicalensis georgi
• rhodiola rosea l
• embryo-toxicity
• teratogenicity
• foetotoxicity
• postnatal development