Nature Communications (Feb 2018)

Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria

  • Thomas Hoffmann,
  • Daniel Krug,
  • Nisa Bozkurt,
  • Srikanth Duddela,
  • Rolf Jansen,
  • Ronald Garcia,
  • Klaus Gerth,
  • Heinrich Steinmetz,
  • Rolf Müller

DOI
https://doi.org/10.1038/s41467-018-03184-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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It is thought that the chances for discovery of novel natural products increase by screening rare organisms. Here the authors analyse metabolites produced by over 2300 myxobacterial strains and, indeed, find a correlation between taxonomic distance and production of distinct secondary metabolite families.