Pifu-xingbing zhenliaoxue zazhi (Apr 2022)

Research progress in pathogenesis of the pyoderma gangrenousum

  • Xiaoli LI,
  • Naiyu LIN,
  • Xuhua TANG,
  • Jiande HAN

DOI
https://doi.org/10.3969/j.issn.1674-8468.2022.02.018
Journal volume & issue
Vol. 29, no. 2
pp. 178 – 181

Abstract

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Pyoderma gangrenosum (PG) is a neutrophilic dermatosis with unknown origin. Genetic factors, neutrophil dysfunction, complement system dysregulation and aberrant cytokine secretion play important parts in its pathogenesis. This article will make a review of the pathogenesis of the pyoderma gangrenosum from the aspects mentioned above.

Keywords