mBio (Apr 2021)

The Architectural Factor HMGB1 Is Involved in Genome Organization in the Human Malaria Parasite Plasmodium falciparum

  • Binbin Lu,
  • Meng Liu,
  • Liang Gu,
  • Ying Li,
  • Shijun Shen,
  • Gangqiang Guo,
  • Fei Wang,
  • Xiaohui He,
  • Yuemeng Zhao,
  • Xiaomin Shang,
  • Liping Wang,
  • Guang Yang,
  • Qianshu Zhu,
  • Jun Cao,
  • Cizhong Jiang,
  • Richard Culleton,
  • Gang Wei,
  • Qingfeng Zhang

DOI
https://doi.org/10.1128/mBio.00148-21
Journal volume & issue
Vol. 12, no. 2

Abstract

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Malaria remains a major public health and economic burden currently. The mutually exclusive expression of the virulence genes is associated with the pathogenesis and immune evasion of human malaria parasites in the host.