Frontiers in Oncology (Jun 2023)

Discrepancies in breast cancer’s oncological outcomes between public and private institutions in the southeast region of Brazil: a retrospective cohort study

  • Diocésio Alves Pinto Andrade,
  • Ana Carolina Veneziani,
  • Carlos Eduardo Paiva,
  • Ricardo dos Reis,
  • Carlos Alberto Fruet Filho,
  • André Octávio Nicolau Sanches,
  • Alison Wagner Azevedo Barroso,
  • Alessandra Caroline Moretto Carbinatto Paz,
  • Georgia Cristina de Mello Kons,
  • Daniel D’Almeida Preto,
  • Maria Carolina Bogoni Budib,
  • Maria Augusta Safro,
  • Gustavo Sanches Faria Pinto,
  • João Paolo Bilibio,
  • Cristiano de Pádua Souza

DOI
https://doi.org/10.3389/fonc.2023.1169982
Journal volume & issue
Vol. 13

Abstract

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BackgroundBrazil is a middle-income country with inequalities in its healthcare system. The disparities between public and private services affect the diagnosis and treatment of patients with breast cancer. The aim of this study is to assess whether disease-free survival (DFS) and overall survival (OS) are different in public and private specialized centers.Patient and methodsA retrospective cohort study with 1,545 breast cancer patients diagnosed from 2003 to 2011 at Barretos Cancer Hospital—BCH (public group, N = 1,408) and InORP Oncoclinicas (private group, N = 137) was conducted. A 1:1 propensity score matching (PSM) analysis was used to adjust the differences between the groups’ characteristics (n = 137 in each group).ResultsThe median age at diagnosis was 54.4 years. Estimated DFS rates at 1, 5, and 10 years were 96.0%, 71.8%, and 59.6%, respectively, at BCH and 97.8%, 86.9%, and 78%, respectively, at InORP (HR: 2.09; 95% confidence interval [CI], 1.41–3.10; p < 0.0001). Estimated OS rates at 1, 5, and 10 years were 98.1%, 78.5%, and 65.4%, respectively, at BCH and 99.3%, 94.5%, and 91.9%, respectively, at InORP (HR: 3.84; 95% CI, 2.16–6.82; p < 0.0001). After adjustment by PSM, DFS and OS results in 1, 3, and 5 years remained worse in the public service compared to the private service.ConclusionPatients treated in a public center have worse DFS and OS after a follow-up period of more than 5 years. These results were corroborated after carrying out the PSM.

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