Gene Promoter Methylation Patterns throughout the Process of Cervical Carcinogenesis

Nan Yang; Esther R. Nijhuis; Haukeline H. Volders; Jasper J. H. Eijsink; Ágnes Lendvai; Bo Zhang; Harry Hollema; Ed Schuuring; G. Bea A. Wisman; Ate G. J. van der Zeea

doi:10.3233/CLO-2009-0510

Cellular Oncology (Jan 2010)

Gene Promoter Methylation Patterns throughout the Process of Cervical Carcinogenesis

Nan Yang,
Esther R. Nijhuis,
Haukeline H. Volders,
Jasper J. H. Eijsink,
Ágnes Lendvai,
Bo Zhang,
Harry Hollema,
Ed Schuuring,
G. Bea A. Wisman,
Ate G. J. van der Zeea

Affiliations

Nan Yang: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Esther R. Nijhuis: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Haukeline H. Volders: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Jasper J. H. Eijsink: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Ágnes Lendvai: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Bo Zhang: Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
Harry Hollema: Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Ed Schuuring: Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
G. Bea A. Wisman: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Ate G. J. van der Zeea: Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

DOI: https://doi.org/10.3233/CLO-2009-0510
Journal volume & issue: Vol. 32, no. 1-2
pp. 131 – 143

Abstract

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Objectives: To determine methylation status of nine genes, previously described to be frequently methylated in cervical cancer, in squamous intraepithelial lesions (SIL).

Published in Cellular Oncology

ISSN: 1570-5870 (Print); 1875-8606 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Science: Biology (General): Cytology
Website: https://www.hindawi.com/journals/acp/

About the journal