Eurasian Journal of Medicine (Apr 2011)
Candida Glabrata Perinephric Abscess
Abstract
Perinephric abscess is a rare complication of urinary tract infections, and the etiology is usually a gram negative bacillus. We report a case of Candida glabrata perinephric abscess in a patient with diabetes mellitus who had a recent episode of pyelonephritis that was treated with antibiotics. Percutaneous drainage and fluconazole treatment led to resolution of the infection. Yeast perinephric abscess should be considered when symptoms of acute or chronic urinary tract infection occur in elderly and diabetic patients, especially patients who are unresponsive to antibacterial therapy. The clinical course is sometimes insidious. Imaging (contrast-enhanced CT or MRI) is required for diagnosis, and drainage is indicated for successful therapy. Adjuvant antifungal treatment is recommended based on the results of antifungal susceptibility tests.